2016

Preservation Analysis of Macrophage Gene Coexpression Between Human and Mouse Identifies PARK2 as a Genetically Controlled Master Regulator of Oxidative Phosphorylation in Humans.

Codoni et al.

G3 (Bethesda). 2016;6(10):3361-3371.

PubMed ID: 27558669

DOI: 10.1534/g3.116.033894

2015

Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism.

Germain et al.

Am J Hum Genet. 2015;96(4):532-42.

PubMed ID: 25772935

DOI: 10.1016/j.ajhg.2015.01.019

2014

Allelic expression mapping across cellular lineages to establish impact of non-coding SNPs.

Adoue et al.

Mol Syst Biol. 2014;10:754.

PubMed ID: 25326100

DOI: 10.15252/msb.20145114

Single nucleotide polymorphisms with cis-regulatory effects on long non-coding transcripts in human primary monocytes.

Almloef et al.

PLoS One. 2014;9(7):e102612

PubMed ID: 25025429

DOI: 10.1371/journal.pone.0102612

A meta-analysis of genome-wide association studies identifies ORM1 as a novel gene controlling thrombin generation potential.

Rocanin-Arjo et al.

Blood. 2014;123(5):777-85.

PubMed ID: 24357727

DOI: 10.1182/blood-2013-10-529628

2013

Male-specific region of the Y chromosome and cardiovascular risk: phylogenetic analysis and gene expression studies.

Bloomer et al.

Arterioscler Thromb Vasc Biol. 2013;33(7):1722-7

PubMed ID: 23640493

DOI: 10.1161/ATVBAHA.113.301608

Large-scale association analysis identifies new risk loci for coronary artery disease.

Deloukas et al.

Nat Genet. 2013;45(1):25-33

PubMed ID: 23202125

DOI: 10.1038/ng.2480

Genome-wide haplotype analysis of cis expression quantitative trait loci in monocytes.

Garnier et al.

PLoS Genet. 2013;9(1):e1003240

PubMed ID: 23382694

DOI: 10.1371/journal.pgen.1003240

2012

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation.

Huang et al.

Blood. 2012;120(24):4873-81

PubMed ID: 22990020

DOI: 10.1182/blood-2012-06-436188

Comprehensive exploration of the effects of miRNA SNPs on monocyte gene expression.

Greliche et al.

PLoS One. 2012;7(9):e45863.

PubMed ID: 23029284

DOI: 10.1371/journal.pone.0045863

Long-range DNA looping and gene expression analyses identify DEXI as an autoimmune disease candidate gene.

Davidson et al.

Hum Mol Genet. 2012;21(2):322-33

PubMed ID: 21989056

DOI: 10.1093/hmg/ddr468

Statistical colocalization of monocyte gene expression and genetic risk variants for type 1 diabetes

Wallace et al.

Hum Mol Genet. 2012;21(12):2815-24

PubMed ID: 22403184

DOI: 10.1093/hmg/dds098

2011

Blood pressure loci identified with a gene-centric array.

Johnson et al.

Am J Hum Genet. 2011;89(6):688-700

PubMed ID: 22100073

DOI: 10.1016/j.ajhg.2011.10.013

Integrating genome-wide genetic variations and monocyte expression data reveals trans-regulated gene modules in humans.

Rotival et al.

PLoS Genet. 2011;7(12):e1002367.

PubMed ID: 22144904

DOI: 10.1371/journal.pgen.1002367

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.

Wain et al.

Nat Genet. 2011;43(10):1005-11

PubMed ID: 21909110

DOI: 10.1038/ng.922

Maps of open chromatin guide the functional follow-up of genome-wide association signals: application to hematological traits.

Paul et al.

PLoS Genet. 2011;7(6):e1002139.

PubMed ID: 21738486

DOI: 10.1371/annotation/5d0c3be4-6f34-420a-960f-0a880bbf6128

A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy.

Villard et al.

Eur Heart J. 2011;32(9):1065-76.

PubMed ID: 21459883

DOI: 10.1093/eurheartj/ehr105

2010

A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk.

Heinig et al.

Nature. 2010;467(7314):460-4

PubMed ID: 20827270

DOI: 10.1038/nature09386

2012

Statistical colocalization of monocyte gene expression and genetic risk variants for type 1 diabetes

Wallace et al.

Hum Mol Genet. 2012;21(12):2815-24

PubMed ID: 22403184

DOI: 10.1093/hmg/dds098

2011

Integrating genome-wide genetic variations and monocyte expression data reveals trans-regulated gene modules in humans.

Rotival et al.

PLoS Genet. 2011;7(12):e1002367.

PubMed ID: 22144904

DOI: 10.1371/journal.pgen.1002367

2017

Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions.

Saleheen et al.

Circulation. 2017;135(24):2336-2353.

PubMed ID: 28461624

DOI: 10.1161/CIRCULATIONAHA.116.022069

Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms.

Howson et al.

Nat Genet. 2017;49(7):1113-1119.

PubMed ID: 4589895

DOI: 10.1038/ng.3874

Identifying systematic heterogeneity patterns in genetic association meta-analysis studies.

Magosi et al.

PLoS Genet. 2017;13(5):e1006755

PubMed ID: 28459806

DOI: 10.1371/journal.pgen.1006755

2016

Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study.

Prins et al.

PLoS Med. 2016;13(6):e1001976.

PubMed ID: 27327646

DOI: 10.1161/10.1371/journal.pmed.1001976

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis.

Loley et al.

Sci Rep. 2016;6:35278.

PubMed ID: 27731410

DOI: 10.1038/srep35278

Common and Rare Genetic Variation in CCR2, CCR5, or CX3CR1 and Risk of Atherosclerotic Coronary Heart Disease and Glucometabolic Traits.

Golbus et al.

Circ Cardiovasc Genet. 2016;9(3):250-8.

PubMed ID: 27013693

PMC ID: 5015681

DOI: 10.1161/CIRCGENETICS.115.001374

2015

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.

Nikpay et al.

Nature genetics 2015;47(10);1121-30.

PubMed ID: 28530674

DOI: 10.1038/ng.3396

Genetically determined height and coronary artery disease.

Nelson et al.

N Engl J Med. 2015;372(17):1608-18.

PubMed ID: 25853659

PMC ID: 4648271

DOI: doi: 10.1038/ng.3396

Effect of Bile Acid Sequestrants on the Risk of Cardiovascular Events: A Mendelian Randomization Analysis.

Ross et al.

Circ Cardiovasc Genet. 2015;8(4):618-27

PubMed ID: 26043746

DOI: 10.1161/CIRCGENETICS.114.000952

Genetic studies of body mass index yield new insights for obesity biology.

Locke et al.

Nature. 2015;518(7538):197-206.

PubMed ID: 25673413

DOI: 10.1038/nature14177

New genetic loci link adipose and insulin biology to body fat distribution.

Shungin et al.

Nature. 2015;518(7538):187-96.

PubMed ID: 25673412

PMC ID: 3679547

DOI: 10.1038/nature14132

2013

Genetic variants from lipid-related pathways and risk for incident myocardial infarction.

Song et al.

PLoS One. 2013;8(3):e60454.

PubMed ID: 23555974

PMC ID: 3612051

DOI: 10.1371/journal.pone.0060454

Common variants associated with plasma triglycerides and risk for coronary artery disease.

Do et al.

Nat Genet. 2013;45(11):1345-52.

PubMed ID: 24097064

PMC ID: 3904346

DOI: 10.1038/ng.2795

Large-scale association analysis identifies new risk loci for coronary artery disease.

Deloukas et al.

Nat Genet. 2013;45(1):25-33

PubMed ID: 23202125

DOI: 10.1038/ng.2480

2017

Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium.

Power et al.

Biol Psychiatry. 2017;81(4):325-335.

PubMed ID: 27519822

DOI: 10.1016/j.biopsych.2016.05.010

Rheumatoid Arthritis and Coronary Artery Disease: Genetic Analyses Do Not Support a Causal Relation.

Jansen et al.

J Rheumatol. 2017;44(1):4-10.

PubMed ID: 27744395

DOI: 10.3899/jrheum.151444

2016

Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk Factors.

LeBlanc et al.

Circ Res. 2016 Jan 8;118(1):83-94.

PubMed ID: 26487741

DOI: 10.1161/CIRCRESAHA.115.306629

2015

Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk.

Jansen et al.

Atherosclerosis. 2015;241(2):419-26.

PubMed ID: 6074316

DOI: 10.1016/j.atherosclerosis.2015.05.033

2013

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.

Koettgen et al.

Nat Genet. 2013;45(2):145-54.

PubMed ID: 23263486

PMC ID: 3663712

DOI: 10.1038/ng.2500

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.

Koettgen et al.

Nat Genet. 2013;45(2):145-54.

PubMed ID: 23263486

PMC ID: 3663712

DOI: 10.1038/ng.2500

Association of genome-wide variation with highly sensitive cardiac troponin-T levels in European Americans and Blacks: a meta-analysis from atherosclerosis risk in communities and cardiovascular health studies.

Yu et al.

Circ Cardiovasc Genet. 2013;6(1):82-8.

PubMed ID: 23247143

PMC ID: 3693561

DOI: 10.1161/CIRCGENETICS.112.963058

Loci influencing blood pressure identified using a cardiovascular gene-centric array.

Ganesh et al.

Hum Mol Genet. 2013;22(8):1663-78.

PubMed ID: 23303523

PMC ID: 3657476

DOI: 10.1093/hmg/dds555

Genetic predisposition to higher blood pressure increases coronary artery disease risk.

Lieb et al.

Hypertension. 2013;61(5):995-1001

PubMed ID: 23478099

PMC ID: 3855241

DOI: 10.1161/HYPERTENSIONAHA.111.00275

Overlap between common genetic polymorphisms underpinning kidney traits and cardiovascular disease phenotypes: the CKDGen consortium.

Olden et al.

Am J Kidney Dis. 2013;61(6):889-98.

PubMed ID: 23474010

DOI: 10.1053/j.ajkd.2012.12.024

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.

den Hoed et al.

Nat Genet. 2013;45(6):621-31

PubMed ID: 23583979

DOI: 10.1038/ng.2610

A systems biology framework identifies molecular underpinnings of coronary heart disease.

Huan et al.

Arterioscler Thromb Vasc Biol. 2013;33(6):1427-34.

PubMed ID: 23539213

PMC ID: 3752786

DOI: 10.1161/ATVBAHA.112.300112

Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia.

Reiner et al.

Hum Mol Genet. 2013;22(16):3381-93.

PubMed ID: 23620142

PMC ID: 3723315

DOI: 10.1093/hmg/ddt189

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.

Sabater-Lleal et al.

Circulation. 2013;128(12):1310-24.

PubMed ID: 23969696

PMC ID: 3842025

DOI: 10.1161/CIRCULATIONAHA

Strategies beyond genome-wide association studies for atherosclerosis.

Maouche S and Schunkert H

Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB) 2012;32(2):170-81.

PubMed ID: 22258900

DOI: 10.1161/ATVBAHA

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.

Mehta NN.

Circ Cardiovasc Genet. 2011;4(3):327-9.

PubMed ID: 21673312

DOI: 10.1161/CIRCGENETICS.111.960443

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.

Schunkert et al.

Nature Genetics 2011;6;43(4):333-8.

PubMed ID: 21378990

PMC ID: 3119261

DOI: 10.1038/ng.784

Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls..

Preuss et al.

Circ Cardiovasc Genet;3(5):475-83.

PubMed ID: 20923989

DOI: 10.1161/CIRCGENETICS.109.899443

2012

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation.

Huang et al.

Blood. 2012;120(24):4873-81

PubMed ID: 22751097

PMC ID: 3520624

DOI: 10.1182/blood-2012-06-436188

Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease.

Lu et al.

Nat Genet. 2012;44(8):890-4

PubMed ID: 22990020

PMC ID: 3927410

DOI: 10.1038/ng.2337

A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex.

Davies et al.

Circ Cardiovasc Genet. 2012;5(2):217-25

PubMed ID: 22319020

PMC ID: 3335297

DOI: 10.1161/CIRCGENETICS.111.961243

2011

Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.

O´Donnell et al.

Circulation. 2011;124(25):2855-64.

PubMed ID: 22144573

PMC ID: 3397173

DOI: 10.1182/blood-2012-06-436188

Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1.

Bown et al.

Am J Hum Genet. 2011;89(5):619-27.

PubMed ID: 22055160

PMC ID: 3213391

DOI: 10.1016/j.ajhg.2011.10.002

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque.

Bis et al.

Nat Genet. 2011;43(10):940-7.

PubMed ID: 21909108

PMC ID: 3257519

DOI: 10.1038/ng.920