Research activities & interests

Current research

Currently, I am working on projects involving development of computational methods in life-sciences and on Data science algorithms using Big Data, BioNLP, cloud-computing and artificial intelligence. I am also working on intelligent integrative knowledge bases for precision medicine and translational research.

Postdoctoral research

On July 1st, 2010, I moved to Germany and started my postdoctoral fellowship at the University of Luebeck, department of Medicine Clinic II (Cardiology; Prof H. Schunkert). My work involved the development of system genetics and integrative approaches in cardiovascular genomics within the CARDIoGRAM consortium.

Research during my PhD

On November 2005, I started my PhD of Bioinformatics at the Pierre Louis Doctoral School of Public Health, Epidemiology and Biomedical Information (Profs A. J. Valleron and D. Costagliola), University Pierre et Marie Curie (Paris VI) under the supervision of Dr F. Cambien.

For my doctoral thesis, I have worked on bioinformatics approaches in cardiovascular research. My work during this period involved the development of bioinformatics approaches for preprocessing, analysis and management of microarray data (trancsriptomics, GWAS, and eQTL data). I was in charge of the Transcriptomic Working Package within the large-scale EU-funded Cardiogenics program in which transcriptomics and eQTL analysis have been performed on human monocytes and macrophages.

Research before my PhD

I performed two Masters of Research and a University Diploma (DU).

Research as part of my Masters of medical informatics and communication technologies

I performed a research training at the European Hospital George Pompidou (HEGP), departments of Radiology (Prof G. Frija) and Medical Informatics (Prof P. Degoulet), and at CIRA (Société de Compression d´Images en Réseaux et Applications), a high-tech Company for image compression and technology of networks (Prof S. Hochberg). I have defended, on 2004, my Master of research thesis entitled "quantitative and visual assessment of a medical image compression algorithm based on wavelet transformation. Elaboration of optimized compression approach". This Matser thesis was supervised by Dr D. Heudes and Mr S. Topin.

My research as part of my DU of Bioengineering, Valorisation of Applied Research and Biomedical Innovation.

I have prepared at the University Paris VI and Diaconesse Hospital in Paris (Prof A. Sezeur) a University Diploma of Bioengineering, Valorisation of Applied Research and Biomedical Innovation. I defended, on 2005, a dissertation entitled "protection of persons in biomedical research : risks related to the introduction of new communication technologies such as wireless and mobile communication".

My research as part of my Masters of research in the history of sciences and technics

My research is focused on the history of reverse engineering and systems biology.

My research as part of my engineering degree in computer sciences

For my engineering research project, I chose to work on networking and TIC in health care. My research took place at the faculties of medicine and sciences of engineering at the university of Constantine.


All projects to which I have contributed : Link

My Research Interests

  • Translational Bioinformatics
  • Big Data in Life-Sciences
  • Cloud Computing
  • Precision Medicine
  • eHealth and Digital Technologies
  • Cardiovascular Genomics
  • Bioinformatics and Computational Biology
  • Transcriptomics and Gene Regulation
  • Whole-Genome/Exome Sequencing
  • Genome-wide Association Studies
  • Genetics of Gene Expression (eQTL)
  • Life-Science Databases and Biological Annotation Metadata
  • Machine Learning and Data Mining
  • Statistic Genetics
  • Biology of Monocytes and Macrophages
  • Systems Biology and Reverse Engineering
  • History of Sciences
  • Research Integrity